Complete Guide to Radiotherapy: Treatment Process, Side Effects & Recovery



Everything you need to know about radiation therapy for cancer treatment - from preparation to recovery and long-term care

Radiotherapy, also known as radiation therapy, is a critical cancer treatment that uses high-energy radiation to destroy cancer cells and shrink tumors. Approximately 50% of all cancer patients receive radiation therapy at some point during their treatment. This comprehensive guide will walk you through everything you need to know about this vital treatment modality.

[Image: Modern radiotherapy machine with patient]
Modern linear accelerator used for external beam radiotherapy

What is Radiotherapy?

Radiotherapy is a localized treatment that uses controlled doses of radiation to kill cancer cells or damage them so they cannot multiply. The radiation damages the DNA inside cells, making it impossible for them to divide and grow. While both cancer and healthy cells are affected by radiation, cancer cells are more vulnerable because they divide more rapidly and are less able to repair themselves.

Key Fact: Radiation therapy can be used as a primary treatment to cure cancer, in combination with other treatments (like chemotherapy or surgery), to reduce the risk of cancer returning after surgery, or to relieve symptoms in advanced cancer (palliative care).

Types of Radiotherapy

1. External Beam Radiotherapy (EBRT)

This is the most common type, where radiation is delivered from outside the body using a machine called a linear accelerator. The machine rotates around you, delivering radiation from different angles to target the tumor while sparing surrounding healthy tissue.

2. Internal Radiotherapy (Brachytherapy)

In this approach, radioactive material is placed inside the body, very close to or inside the tumor. This allows a high dose of radiation to reach a small area. Common for prostate, cervical, and some breast cancers.

3. Systemic Radiotherapy

Radioactive drugs are given by mouth or injection to treat certain types of cancer. These drugs travel throughout the body to target cancer cells. Used for thyroid cancer, some types of lymphoma, and bone metastases.

[Image: Comparison of different radiotherapy techniques]
Different radiotherapy techniques: external beam, brachytherapy, and systemic radiation

The Radiotherapy Process: Step by Step

Step 1: Consultation and Planning

Your radiation oncologist will review your medical history, perform a physical exam, and discuss the potential benefits and risks. If radiotherapy is recommended, a planning session (simulation) will be scheduled.

Step 2: Simulation and Treatment Planning

During simulation, you'll be positioned exactly as you will be during treatment. Immobilization devices (like masks or molds) may be created to help you stay still. CT scans are taken to create a 3D model of the treatment area. This process can take 30 minutes to 2 hours.

Step 3: Treatment Planning by the Team

Your radiation oncologist, medical physicist, and dosimetrist work together to create a customized treatment plan. They determine the optimal radiation dose, beam angles, and techniques to maximize tumor damage while minimizing effects on healthy tissue.

Step 4: Treatment Delivery

Treatments are usually given daily, Monday through Friday, for 2 to 8 weeks. Each session typically lasts 15-30 minutes, though most of this time is for positioning. The actual radiation delivery takes only 1-5 minutes. The treatment is painless, like having an X-ray.

Step 5: Follow-up Care

After treatment completion, regular follow-up appointments will monitor your recovery, check for side effects, and assess treatment effectiveness.

Important: It's crucial to attend all scheduled radiotherapy sessions. Missing treatments can reduce the effectiveness of your therapy and may require adjustments to your treatment plan.

Common Side Effects of Radiotherapy

Side effects depend on the treatment area, radiation dose, and individual factors. They typically develop gradually over the course of treatment.

Treatment Area Common Side Effects Management Tips
Head & Neck Sore throat, mouth ulcers, dry mouth, taste changes, fatigue Soft foods, oral care routines, saliva substitutes
Chest Difficulty swallowing, cough, shortness of breath Small frequent meals, cough suppressants as prescribed
Abdomen/Pelvis Nausea, diarrhea, bladder irritation, fatigue Diet modifications, anti-nausea medication, hydration
Breast Skin redness/irritation, breast swelling, fatigue Gentle skin care, loose clothing, proper support
Brain Hair loss, headaches, fatigue, memory changes Head coverings, rest, cognitive exercises
[Image: Patient managing skin care during radiotherapy]
Proper skin care is essential during radiotherapy to minimize skin reactions

Advanced Radiotherapy Techniques

Intensity-Modulated Radiation Therapy (IMRT)


Uses computer-controlled linear accelerators to deliver precise radiation doses to malignant tumors. The radiation intensity is modulated across each beam, allowing higher doses to the tumor while sparing nearby healthy tissue.

Stereotactic Radiosurgery (SRS) and Radiotherapy (SRT)

Delivers very high doses of precisely targeted radiation using extremely detailed imaging. Often used for brain tumors and other small tumors. Can be completed in 1-5 sessions instead of traditional multi-week courses.

Proton Beam Therapy

Uses protons rather than X-rays to treat cancer. Protons stop at the tumor, potentially reducing damage to healthy tissue beyond the tumor. Particularly beneficial for children and tumors near critical structures.

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Recovery and Long-Term Care

Recovery from radiotherapy varies by individual and treatment area. Side effects typically peak toward the end of treatment and gradually improve over the following weeks. Some tips for recovery:

  • Rest: Fatigue is common - listen to your body and allow time for recovery
  • Nutrition: Eat a balanced diet to support healing
  • Skin Care: Continue gentle skin care even after treatment ends
  • Follow-up: Attend all scheduled follow-up appointments
  • Support: Seek emotional support through counseling or support groups

Spome side effects may be long-term or develop months to years after treatment (late effects). Your oncology team will monitor you for these and help manage any that occur.


© 2026 Cancer Treatment Guide. All rights reserved. | This content is designed for educational purposes.

Last updated: June 2026 | For medical advice, please consult a healthcare professional

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